Approximately 55,000 people are diagnosed with colorectal cancer in Germany each year. About a quarter of these cases develop from a specific type of colorectal polyp (so-called serrated lesions). These precursor lesions often carry a mutation in the BRAF gene and lead to particularly aggressive tumors that respond poorly to existing therapies.Until now, the molecular changes leading to the development of this subgroup of colorectal cancer and t…
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