Colorectal Tumors May Damage Nerves Before Chemotherapy

Colorectal tumors may damage nerves before chemotherapy

Researchers at The University of Texas MD Anderson Cancer Center found that, in preclinical models of colorectal cancer, tumors can start damaging peripheral nerves before chemotherapy begins.

Colorectal Cancer May Damage Nerves Before Chemotherapy Begins

Researchers at The University of Texas MD Anderson Cancer Center have discovered that colorectal tumors may begin damaging peripheral nerves before patients receive chemotherapy, challenging the widely held assumption that cancer-related neuropathy is primarily a consequence of treatment. In preclinical models, tumors were linked to subtle inflammation, loss of nerve fibers, impaired electrical signaling and injury to myelin—the insulating mater…

Colorectal Cancer May Quietly Damage Nerves Prior to Chemotherapy

Researchers at The University of Texas MD Anderson Cancer Center found that, in preclinical models of colorectal cancer, tumors can start damaging peripheral nerves before chemotherapy begins.