The Gordon Memorial Lecture: A paradigm shift in high pathogenicity avian influenza and perspectives for the future Since 2020, H5 high pathogenicity avian influenza (HPAI) viruses of clade 2.3.4.4b have spread rapidly to all continents except Oceania. This panzootic presents an unprecedented threat to global poultry health, with severe uncertainties as to when it will peak or resolve. The complex epidemiology across multiple ecosystems creates …
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