The African swine fever virus MGF505-1R protein recruits the cullin-RING-ligase machinery to promote p300 degradation

Researchers found that African swine fever virus pA151R inhibits stress granule formation and host protein synthesis by disrupting mRNA nuclear export

The African swine fever virus MGF505-1R protein recruits the cullin-RING-ligase machinery to promote p300 degradation

The African swine fever virus MGF505-1R protein recruits the cullin-RING-ligase machinery to promote p300 degradation AbstractAfrican swine fever virus (ASFV) is a large, complex DNA virus that causes a haemorrhagic disease with lethality rates approaching 100%. Mechanisms of virulence are still poorly understood, but loss of members of the multigene families (MGF) is commonly observed in naturally occurring attenuated virus strains, indicating …