Study reveals how female hormones trigger opioid production for pain suppression

Estrogen may spur the body to make opioids after injury

The female sex hormone estrogen, along with progesterone, appears to underlie a fundamental difference in how males and females process pain, a mouse study finds.

Study reveals how female hormones trigger opioid production for pain suppression

Scientists have discovered a new mechanism that acts via an immune cell and points toward a different way of treating chronic pain.

Immune cells have unexpected role in fighting pain

Inflammation-suppressing regulatory T cells reduce pain in female mice by targeting nerve cells

Estrogen and Progesterone Regulate Natural Opioids in Women

UCSF research reveals that female hormones regulate T-regs in the meninges to produce natural opioids, offering new possibilities for non-opioid pain relief.