Neural Stem Cell Grafts Show Promise for Myelin Repair in Multiple Sclerosis

Neural stem cell grafts show promise for myelin repair in multiple sclerosis

A study led by Cambridge researchers has shed light on how neural stem cell grafts could help restore myelin in the central nervous system.

Neural Stem Cell Grafts Restore Myelin in MS-Like Lesions in Mice

A new study led by scientists at the University of Cambridge has shown that induced neural stem cell (iNSC) grafts can successfully generate myelin-producing cells in mice with lesions similar to those seen in progressive multiple sclerosis (MS). The research, published in the journal Brain, marks the first time that stem cell grafts have been shown to directly replace lost oligodendrocytes to promote remyelination in the central nervous system …

Stem cell sleep deprivation

Tweet Could sleep deprivation be the reason stem cell therapy fails in some cases? It appears so. In a recent study using the mouse Cuprizone (demyelination model), it was shown that sleep-deprived bone marrow-derived mesenchymal stem cells (BMSCs) were significantly less effective than their well-rested counterparts in preserving their regenerative capabilities. Differences were noted in both motor behavioural recovery of the mice and histologi…

Stem Cell Grafts Show Promise in Repairing Myelin in MS

A new study reveals that neural stem cell grafts can generate new myelin in the central nervous system, offering hope for treating progressive multiple sclerosis (MS). Researchers showed that induced neural stem cells matured into myelin-producing oligodendrocytes and safely integrated into damaged regions in a mouse model.