Semaglutide to Reduce Calorie Intake Slows Aging in Female Mice, as Might Be Expected
4 Articles
4 Articles
Semagglutide, the active ingredient in drugs like Ozempic and Wegovy, which millions of people use for weight loss and diabetes treatment, has been found to prolong life expectancy.
A study in elderly mouse C57BL/6 found that semaglutide reduced calorie intake by 24% and extended life approximately 12%, with effects similar to caloric restriction in several markers of aging. Researchers warn that prolonged clinical studies are still needed to determine if this benefit can be transferred to humans.
Semaglutide to Reduce Calorie Intake Slows Aging in Female Mice, as Might be Expected
Without careful study design, studies in which the use of GLP-1 receptor agonists such as semaglutide lowered calorie intake significantly via suppression of appetite might be expected to teach us little that we did not already know. Reducing calorie intake without compromising minimum necessary levels of essential nutrients slows aging and extends life, whether achieved via limiting food availability or by limiting appetite. Researchers know th…
A new study in Nature with Danish participation shows that the weight loss molecule semaglutide increases the production of life-extending proteins in older mice. However, the experiment has not yet been performed on humans.
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