Self-dispersible eutectic mixtures with fenofibrate and ibuprofen: Processability and API particle size - Pharma Excipients

Self-dispersible eutectic mixtures with fenofibrate and ibuprofen: Processability and API particle size - Pharma Excipients

Abstract In order to increase the dissolution rate of poorly water-soluble drugs, the preparation of eutectics is a practical way to minimize the drug particle size without the need of grinding and handling of poorly flowing powders. The use of solid self-dispersible excipients as a component of the eutectic may further enhance the drug dissolution rate. In the current study, phase diagrams of eutectic mixtures of polyethylene glycol stearates …