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Resistance mechanism in chronic lymphocytic leukemia identified - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo des Deutschen KrebsforschungszentrumLogo der Deutschen Zentren der GesundheitsforschungLogo des Helmholtzinstitut
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Resistance mechanism in chronic lymphocytic leukemia identified - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo des Deutschen KrebsforschungszentrumLogo der Deutschen Zentren der GesundheitsforschungLogo des Helmholtzinstitut
The drug ibrutinib is a Bruton's tyrosine kinase (BTK) inhibitor. These agents, which have only been available for about ten years, have significantly improved the treatment options for chronic lymphocytic leukemia: BTK inhibitors have a targeted effect on the malignant B cells in CLL. They slow down their uncontrolled proliferation by blocking the Bruton's tyrosine kinase. This enzyme plays an important role in the maturation and proliferation o
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