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Reactive stroma as a prognostic biomarker of metastasis in patients with breast cancer: integration of histopathology and transcriptomic profiling
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Reactive stroma as a prognostic biomarker of metastasis in patients with breast cancer: integration of histopathology and transcriptomic profiling
Background: The tumor stroma plays a pivotal role in cancer progression, but its prognostic relevance remains underexplored in clinical settings. This study evaluated whether histologically defined reactive stroma, a fibrotic and collagen-rich microenvironment, serves as a pro...
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