Boosting Enzyme in Brain Immune Cells Could Help Treat Alzheimer's Disease

Boosting enzyme in brain immune cells could help treat Alzheimer's disease

In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin-converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease. Their findings, published in Nature Aging, could lead to cellular therapies to help treat the disease in humans.

Boosting a brain enzyme may help reverse Alzheimer’s damage, study suggests

Scientists at Cedars-Sinai have found a way to restore the function of key brain immune cells in mice with Alzheimer’s disease—an advance that could lead to new treatments for humans. Their study, published in Nature Aging, shows that increasing the amount of a specific enzyme, called angiotensin-converting enzyme (ACE), in brain immune cells known as […] The post Boosting a brain enzyme may help reverse Alzheimer’s damage, study suggests appear…

Enhanced brain immune cells may combat Alzheimer's

A potential new strategy against Alzheimer’s disease is taking shape in the brain’s own defense system. By boosting a specific enzyme in the brain’s immune cells, researchers at Cedars-Sinai have dramatically reduced the hallmark plaques of Alzheimer’s and reversed cognitive decline in mice. The news opens the door to potential cellular therapies for a disease… The post Revitalizing the brain’s ‘housekeepers’ to combat Alzheimer’s appeared first…

Preclinical Study: Enzyme Could Help Treat Alzheimer’s Disease

In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease.