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PowderInjector microneedles: smart cavity microneedles as a novel intradermal delivery system for high doses of niacinamide
Summary by Pharma Excipients
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1 Articles
PowderInjector microneedles: smart cavity microneedles as a novel intradermal delivery system for high doses of niacinamide
Abstract Niacinamide (NIA) is widely used in cosmetic formulations due to its anti-inflammatory and antioxidant properties. However, its hydrophilic nature (log p = − 0.35) limits penetration through the stratum corneum (SC), necessitating advanced delivery systems. While formulation-enhancement technologies (penetration enhancers, liposomes) still face the SC diffusion barrier, dissolving microneedles (DMNs) bypass the SC. As micron-scale need…
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