Phenylacetic Acid Produced by Gut Microbes Harms the Vascular Endothelium

Phenylacetic Acid Produced by Gut Microbes Harms the Vascular Endothelium

The balance of microbial populations making up the gut microbiome shifts with age. Inflammatory species and those generating harmful metabolites increase in number at the expense of species that generate beneficial metabolites. This is why approaches that rejuvenate the gut microbiome, forcing it back into a more youthful balance of populations, produce significant gains in health and life span in animal studies conducted to date. Here, research…