NOX-1 identified as key molecular target to prolong ketamine's antidepressant effects

Blocking NOX-1 enzyme may extend ketamine's antidepressant effects

Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks. Now, researchers from Japan have identified the enzyme NOX-1 as a key molecular target to prolong ketamine's antidepressant effects.

NOX-1 identified as key molecular target to prolong ketamine's antidepressant effects

Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks.

Blocking NOX-1 Extends Ketamine’s Effectiveness for Depression

Researchers have identified the NOX-1 enzyme as the reason ketamine's antidepressant effects are short-lived. By blocking NOX-1, they extended the drug's benefits from days to weeks.

This drug could reduce suicidal thoughts quickly

A new study from Columbia University has brought hopeful news for people struggling with severe depression and suicidal thoughts. Researchers have found that ketamine, a drug already used in medicine for anesthesia and depression, can quickly reduce suicidal thinking while also improving a person’s ability to think clearly and make decisions. This discovery is important […] The post This drug could reduce suicidal thoughts quickly appeared first…