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Obesity Can Raise Colorectal Cancer Risk by 30–50%, Study Finds
5 Articles
5 Articles
Obesity can raise colorectal cancer risk by 30–50%, study finds
Colorectal cancer (CRC) remains one of the leading causes of cancer-related deaths worldwide. While genetics and age are well-known risk factors, growing evidence highlights a significant connection between obesity and colorectal cancer. Understanding this link is crucial in shaping effective prevention and early detection strategies.
Single-cell and Spatial Transcriptomic Mapping Reveals MSEC-myoCAF Interactions Driving Lymph Node Metastasis in Colorectal Cancer
Lymph node metastasis (LNM) is a major determinant of poor prognosis in colorectal cancer (CRC), yet the cellular and spatial mechanisms driving metastatic initiation remain poorly defined. Here, we performed integrative single-cell RNA sequencing (scRNA-seq; 84,735 cells) and spatial transcripto...
Every year, thousands of new cases of colorectal cancer are detected, sometimes too late. If this disease is often associated with age, the number of cases has exploded in recent years. Unfortunately, their symptoms are sometimes ignored or misinterpreted, delaying diagnosis and management. Chris Kirt's story, diagnosed at 31, illustrates the drifts of a medical system that neglects certain profiles. Looking back on his experience, he recalls th…
A clinical trial of Vall d’Hebron Hospital in Barcelona, Spain, showed that a new combination of drugs is able to successfully attack genetic alterations for a metastatic colorectal cancer subtype. “A statistically and clinically significant benefit in overall survival is observed with the experimental combination, which doubles that achieved with standard treatment, the research indicated.
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