Nanozyme-Powered TB Test Enhances Detection for HIV Co-Infection

Performance of the low-cost phenotypic thin-layer agar MDR/XDR-TB Colour Test (first generation, 1G, Color Plate Test) for identifying drug-resistant Mycobacterium tuberculosis isolates in a resource-limited setting

Background: The accessible, easy to use and timely, diagnosis of tuberculosis (TB) drug-susceptibility, including multi-drug resistant (MDR-) TB and extensively-drug resistant (XDR-)TB is often challenging, particularly in resource-constrained settings. We therefore evaluated the...

Nanozyme-Powered TB Test Enhances Detection for HIV Co-Infection

When threatened, the bombardier beetle launches a noxious chemical spray by combining two compounds in its abdomen—a natural defense mechanism that doesn’t require external power. It was this beetle’s ingenuity that inspired scientists to tackle one of the deadliest infectious threats today: tuberculosis (TB), especially in people living with HIV. To circumvent the need for electricity in remote or resource-limited settings, researchers at Tulan…