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JCI The science of safety: adverse effects of GLP-1 receptor agonists as glucose-lowering and obesity medications
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JCI The science of safety: adverse effects of GLP-1 receptor agonists as glucose-lowering and obesity medications
GLP-1 receptor agonist (GLP-1RA) medications have transformed the treatment of type 2 diabetes (T2D) and obesity, with robust evidence for cardiovascular and renal benefits. Nevertheless, GLP-1RA therapy is associated with a pattern of adverse events affecting their safety and tolerability. Here, we delineate mechanisms potentially leading to adverse responses to GLP-1RAs, describe the impact of side effects on treatment persistence, discuss pot…
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