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JCI The promise of GLP-1 receptor agonists for neurodegenerative diseases
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JCI The promise of GLP-1 receptor agonists for neurodegenerative diseases
Glucagon-like peptide-1 receptor agonists (GLP-1RAs), established therapies for type 2 diabetes and obesity, are increasingly recognized for their potential in neurodegenerative diseases. Preclinical studies across diverse neurodegenerative conditions consistently demonstrate neuroprotective effects of GLP-1RAs, including reduced protein aggregation, enhanced autophagy, improved mitochondrial function, suppression of neuroinflammation, and prese…
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