Glycogen Metabolism in Neurons Emerges as Key to Fighting Alzheimer's

Brain sugar glycogen helps manage oxidative stress, may slow Alzheimer’s disease: Study

Findings suggest boosting glycogen breakdown may reduce neurodegeneration linked to Alzheimer’s, dementia - Anadolu Ajansı

Glycogen metabolism in neurons emerges as key to fighting Alzheimer's

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

Scientists discover sugar’s surprising role in Alzheimer’s and dementia

A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s treatments. In a new study published in Nature Metabolism, researchers uncovered a powerful connection between sugar storage in neurons and the progression of brain diseases like Alzheimer’s and frontotemporal dementia. The research, led by scientists at the Buck Institute for Research on Aging, reveals that a form of stored sug…

Insulin Resistance and Alzheimer's Disease

Researchers have considered a role for dysregulation of insulin metabolism in the development of Alzheimer's disease, to the point of suggesting that it might be classified as a type 3 diabetes. Epidemiological data shows that Alzheimer's is nowhere near as clearly a direct, reliable consequence of obesity and consequent metabolic dysfunction as is the case for type 2 diabetes, however, indicating that the story is probably more complex. Here, r…