Xylitol May Be Linked to Major Cardiovascular Events, Study Suggests
Researchers found a stepwise rise in cardiovascular events across blood xylitol levels in two cohorts of 17,710 adults.
- New research found that people with the highest blood levels of xylitol had a 57 percent higher risk of major adverse cardiovascular events over six years than those with the lowest levels.
- The National Institutes summarized research showing xylitol increases platelet sensitivity to clotting signals, with blood levels rising roughly 1,000 fold within 30 minutes of consuming a xylitol-sweetened beverage.
- In a second cohort followed for 30 years, the European Prospective Investigation into Cancer study in Norfolk, England, found an 18 percent increase in risk, though both cohorts were observational and cannot establish causality.
- Full peer-reviewed publication of this specific analysis has not been announced, but Presenter Marco Witkowski of Charité University Hospital in Berlin said findings highlight "how little we know about the cardiovascular safety of xylitol."
- Xylitol remains an approved food additive in the United States, and no regulator has announced a review, though the sweetener appears in sugar-free gum, mints, candies, and toothpaste.
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40 Articles
This Common Sugar Substitute in Gum and Soda Is Linked to Heart Attack & Stroke Risk
If you’ve ever browsed the “sugar-free” snack aisle wondering: Is this really healthier for me? You were right to question it. New research is showing that one of the most popular artificial sweeteners might be doing your body more harm than good. A long-term study presented at the European Society of Cardiology analyzed data from […]
New research confirms the link between xylitol and heart risk, but cardiologist says there's still no reason to worry about regular use of xylitol chewing gum.
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Study Links High Xylitol Levels to Increased Risk of Heart Attack, Stroke and Death
People with the highest blood concentrations of xylitol were more likely to experience major cardiovascular events over long-term follow-up, according to an observational study involving more than 17,000 adults, though researchers cautioned that the findings do not prove the popular sugar substitute causes heart disease.
Is Sugar Really the Biggest Risk to Your Health? A 30-Year Study Linked This Ingredient to More Heart Attacks and Strokes
A study of 17,710 people found that those with higher blood levels of a common sweetener were at increased risk of a major cardiovascular event.
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