Gallic Acid-Loaded Transethosomal Gel for Enhanced Topical Delivery and Sustained Therapeutic Efficacy in Psoriasis Management: Formulation, Optimization, In Vitro and Ex Vivo Assessment - Pharma Excipients

Gallic Acid-Loaded Transethosomal Gel for Enhanced Topical Delivery and Sustained Therapeutic Efficacy in Psoriasis Management: Formulation, Optimization, In Vitro and Ex Vivo Assessment - Pharma Excipients

Abstract Psoriasis is a chronic, non-communicable inflammatory skin disorder for which current treatments are largely limited to symptomatic management. These approaches were often challenged with limitations like inadequate skin penetration, frequent dosing requirements, potential toxicity, and low patient adherence, ultimately compromising therapeutic outcomes and affecting patients’ health. To obviate the flaws that are hindering the clinical…