Fifteen Questions: David Sinclair on Age Reversal, Exercise, and Immortal Yeast Cells

Fifteen Questions: David Sinclair on Age Reversal, Exercise, and Immortal Yeast Cells

The Professor of Genetics sat down with Fifteen Minutes to discuss anti-aging research, the wellness industry, and his grandmother.

Excess Lipids in Muscle Cells as a Contribution to Muscle Aging

Repair Biotechnologies, the company I co-founded, develops therapies based on the ability to selectively clear only excess cholesterol inside cells. This is normally an undruggable target. Cholesterol is essential to cell function, but expensive to manufacture. Species evolved a central factory for cholesterol production, the liver, and a complicated system of distribution that delivers cholesterol to and from the liver as needed. The vast major…