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Evaluating dosing accuracy and galenic dispersion quality in Hospital-Based pediatric spironolactone oral suspension - Pharma Excipients
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Evaluating dosing accuracy and galenic dispersion quality in Hospital-Based pediatric spironolactone oral suspension - Pharma Excipients
Abstract Compounded oral suspensions of spironolactone are commonly used in pediatric patients with heart conditions. However, due to its poor solubility in water, spironolactone suspensions may lead to sedimentation, compromising homogeneity and dose accuracy. This study aimed to assess dose accuracy of spironolactone suspension in critical care settings. Over one month in 2020 and 2022, samples prepared by nurses in Pediatric (PICU) and Neonat…
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