EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis
Summary by elifesciences.org
1 Articles
1 Articles
EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis
Idiopathic scoliosis (IS) is the most common form of spinal deformity with unclear pathogenesis. In this study, we first reanalyzed the loci associated with IS, drawing upon previous studies. Subsequently, we mapped these loci to candidate genes using either location-based or function-based strategies. To further substantiate our findings, we verified the enrichment of variants within these candidate genes across several large IS cohorts encompa…
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