The First Vaccine Built for This Ebola Strain Has Entered Human Testing as the DRC Outbreak Becomes the Country's Largest
The Phase 1 study will test safety and immune response in 50 healthy adults as WHO says the outbreak has reached 3,748 confirmed cases.
- The World Health Organization reports that experimental treatments and vaccines for the Bundibugyo strain of Ebola are advancing rapidly in the Democratic Republic of Congo , where the ongoing outbreak is the largest ever recorded.
- This epidemic is caused by the rare Bundibugyo virus, for which no vaccines or treatments are approved, unlike the Zaire Ebola species targeted by existing products like Ervebo.
- Epidemic Preparedness Innovations is funding three vaccine candidates, including Moderna's mRNA candidate and an Oxford chimpanzee adenovirus vector, with investments reaching roughly $62 million.
- The first Phase 1 clinical trial launched by Oxford in mid-July assesses safety in 50 healthy adults aged 18 to 55, though these studies do not yet confirm whether the vaccine prevents disease.
- No vaccine is available for public use or travel protection, and the CDC maintains entry restrictions and screening protocols for travelers from affected regions, with 21 days of symptom monitoring required afterward.
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20 Articles
Studies on drugs and vaccines against the Bundibugyo variant of the Ebola virus have begun, while the WHO warns against the still rapid spread of the disease in the Democratic Republic of Congo.
The Ebola epidemic is not under control, without vaccine the containment becomes difficult. Vaccine expert Richard Hatchett explains how much hope rests on a now tested vaccine.
Red Cross staff disinfect Rwampara hospital in the Democratic Republic of the Congo REUTERS/Gradel Muyisa Mumbere Tests for experimental treatments, preventive medicines and vaccines against the Ebola Bundibugyo strain, responsible for the ongoing outbreak in the Democratic Republic of the Congo (DRC), are advancing rapidly, the World Health Organization (WHO) informed on Tuesday (4). The epidemic — the second largest and fastest spread ever rec…
WHO calls for response scale-up as DRC Ebola cases hit record high
Ebola outbreak: WHO relies on new medicines and vaccines, but those affected still have to be patient despite promising data.
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