Mycobacterium Tuberculosis Biology, Pathogenicity and Interaction with the Host

Mycobacterium tuberculosis biology, pathogenicity and interaction with the host

Since the release of the first Mycobacterium tuberculosis genome in 1998, major advances have been made in understanding the biology of this pathogen, the leading infectious cause of death in modern human history. In this Review, we outline the physiological and metabolic features thought to underpin the survival, evasion and subversion strategies employed by M. tuberculosis as it drives a cycle of transmission, infection and disease in its oblig

University of Otago Researchers Investigate Drug Resistance Mechanisms in Tuberculosis

Researchers from the University of Otago have contribut […] The post University of Otago Researchers Investigate Drug Resistance Mechanisms in Tuberculosis first appeared on GeneOnline News. The post University of Otago Researchers Investigate Drug Resistance Mechanisms in Tuberculosis appeared first on GeneOnline News.

Detection of aerosolized Mycobacterium tuberculosis DNA from adults being investigated for pulmonary tuberculosis using an electrostatic sampler in a South African primary care setting

Background Non-sputum-based diagnosis of tuberculosis is a public health priority. Little is known about the feasibility of detecting Mycobacterium tuberculosis complex (Mtb) DNA in respiratory aerosols in primary care, its diagnostic value, and clinical and microbiolo...