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Chrissy Metz, Serena Williams and Oprah Winfrey Are Just Some of the Stars Using Weight Loss Drugs

Summary by E! News
Chrissy Metz told E! News she was reluctant to give GLP-1s a shot. Serena Williams, as well. But now that the weight loss medications have served up results, they and other celebs are telling all.

2 Articles

Lean Right

The subject ceased to appear only in offices and became part of the conversations about body, health and aging. Among celebrities, the use of GLP-1 class drugs for weight control has been gaining space, with reports ranging from positive results to side effects and questions about aesthetic pressure. Now, Chrissy Metz, known as "This Is Us" and "The Hunting Wives", entered this conversation when he revealed that he decided to resort to treatment…

·Rio de Janeiro, Brazil
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E! News broke the news in Universal City, United States on Saturday, August 15, 2026.
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