CAR-T design: Elements and their synergistic function

CAR-T design: Elements and their synergistic function

Chimeric antigen receptor (CAR) T cells use re-engineered cell surface receptors to specifically bind to and lyse oncogenic cells. Two clinically appr…

Johnson & Johnson has announced the price and reimbursement of the Carvykti National Health System (ciltacabtagen autoleucel; cilta-cel) for the treatment of adult patients with relapsed and refractory multiple myeloma (RMRR) who have received at least one previous treatment (including an immunomodulatory agent (IMiD) and a protease inhibitor (PI), have had disease progression to the last treatment and are refractory to lenalidomide.

This Wednesday, we learned that the Hospital Clínic de Barcelona has already treated a total of 502 patients with CAR-T therapy over the course of six years, mostly people with resistant cancer that did not respond to other […]