A Multicentre Validation Study of the Diagnostic Value of Plasma Neurofilament Light

A multicentre validation study of the diagnostic value of plasma neurofilament light

Increased cerebrospinal fluid neurofilament light (NfL) is a recognized biomarker for neurodegeneration that can also be assessed in blood. Here, we investigate plasma NfL as a marker of neurodegeneration in 13 neurodegenerative disorders, Down syndrome, depression and cognitively unimpaired controls from two multicenter cohorts: King’s College London (n = 805) and the Swedish BioFINDER study (n = 1,464). Plasma NfL was significantly increased i…

Can Neurofilament Monitoring Become Standard

During COVID-19 there was a race to make assays for the assessment of SARS-CoV-2 infection and vaccination response and it was a case of mine is better than yours but what ProfAngry and I realised …