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A Novel Approach to Thermogenesis Without Involving Uncoupling Protein 1

Summary by fightaging.org
Mitochondrial uncoupling is the process by which mitochondria in cells switch from producing the chemical energy store molecule adenosine triphosphate (ATP) to releasing that energy as heat. This is of interest in the context of aging because upregulation of mitochondrial uncoupling via a range of strategies appears to somewhat slow aging in animal studies. Sustained upregulation of mitochondrial uncoupling also produces a reduction in fat tissu…
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fightaging.org broke the news in on Wednesday, July 2, 2025.
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