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Top Endpoints News News

FDA approves Moderna’s new lower-dose COVID-19 vaccine

FDA · United States

FDA approves Moderna’s new lower-dose COVID-19 vaccine

59% Center coverage: 129 sources

US court won't lift judge's block on Trump's government overhaul

US Politics · United States

US court won't lift judge's block on Trump's government overhaul

64% Center coverage: 122 sources

A U.S. appeals court on Friday refused to pause a judge's ruling blocking President Donald Trump's administration from carrying out mass layoffs of federal workers and a restructuring of government agencies as part of a sweeping government overhaul.See the Story

Gilead's Trodelvy, with Keytruda, cuts breast cancer risk by 35% in trial

Breast Cancer · United States

Gilead's Trodelvy, with Keytruda, cuts breast cancer risk by 35% in trial

70% Center coverage: 17 sources

Gilead Sciences´ Trodelvy in combination with Merck's blockbuster immunotherapy Keytruda lowered the risk of an aggressive type of breast cancer worsening by 35% when used as an initial treatment, according to results of a large trial presented on Saturday. The data is likely to change how patients are treated following a diagnosis for advanced triple-negative breast cancer, one expert said.See the Story

New three-drug combination could help women with aggressive breast cancer live longer, study suggests

57% Center coverage: 7 sources

NHS · United Kingdom See the Story

ADC-Pertuzumab Promising as New Standard in HER2-Positive Metastatic Breast Cancer

100% Center coverage: 2 sources

(MedPage Today) -- CHICAGO -- First-line trastuzumab deruxtecan (T-DXd) combined with pertuzumab (Perjeta) improved progression-free survival (PFS) in HER2-positive locally advanced or metastatic breast cancer, according to the DESTINY-Breast09...Breast Cancer See the Story

Korean startup Curogen seeks global expansion, new funding to back autoimmune drugs

A South Korean biotech working on multi-specific autoimmune disease treatments is looking to make a leap into the US. Curogen, based in Seoul and backed by local investors, announced Monday that it plans to open ...Seoul · Seoul See the Story

Phase 3 or bust: Why Lilly won't run mid-stage cancer trials

CHICAGO — Self-described “blunt pharma executives” Jake Van Naarden and David Hyman of Eli Lilly sat down Sunday with Endpoints News at the annual ASCO conference. The biggest takeaway from a conversation with the Indianapolis ...Eli Lilly · Indianapolis See the Story

Kymera Reports Early-Stage Success for Drug Meant to Rival Sanofi and Regeneron’s Dupixent

100% Center coverage: 1 sources

A new study finds preliminary signs the therapy might tamp down a class of immune signals linked with chronic conditions.Cambridge, Massachusetts · Cambridge See the Story

Vera Drug Scores in Closely Watched Study in Rare Kidney Disease

100% Center coverage: 2 sources

Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.Innovation See the Story

ASCO 25: AZ Pitches Upfront Oral SERD Use in Breast Cancer

100% Center coverage: 1 sources

AstraZeneca stakes a claim to first-line treatment of HR+ breast cancer with its oral SERD, as Arvinas/Pfizer reveal their second-line dataBreast Cancer See the Story

In race with Merus, Bicara makes the case for two-year survival data

CHICAGO — Forced to play defense after its stock price fell 40% last month on competing data, Bicara hopes to win back some favor with new results for its head and neck cancer drug. In the ...Chicago, IL · Chicago See the Story

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