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Top biopatrika.com News

Specialized T Cells Help Maintain Maternal–Fetal Peace in Pregnancy - BioPatrika

Regulatory KIR⁺CD8⁺ T Cells Rise During Pregnancy to Help Balance Immunity Pregnancy creates a fascinating immunological paradox — the mother’s immune system must tolerate a fetus that is genetically different (semiallogeneic) while still staying alert to infections. A new study in Science Translational Medicine by Li et al. uncovers an important player in this delicate […] The post Specialized T Cells Help Maintain Maternal–Fetal Peace in Pregn…Read Article

Science

Targeted Nanopore Sequencing for HPV Integration in Cervical Cancer - BioPatrika

Research Summary: We developed a cost-effective targeted nanopore sequencing method to identify HPV integration sites in cervical cancers, revealing functional impacts on nearby cancer-related genes and improving diagnostics potential. Author interview Preetiparna Parida is a PhD researcher at MAHE, specializing in viral oncology, nanopore sequencing, and liquid biopsy approaches for HPV-related cervical cancer diagnostics and […] The post Targ…Manipal · Manipal Read Article

enFnCas9: Precision tool for next-generation genome engineering - BioPatrika

enFnCas9: CrisprBits’ licensed precision tool for next-generation genome engineering from India Source: Nature Communications – Read the study When it comes to genome editing, the choice of Cas nuclease can make all the difference between a promising experiment and a clinical breakthrough. Among the growing family of engineered Cas proteins, enhanced Francisella novicida Cas9 (enFnCas9) […] The post enFnCas9: Precision tool for next-generation g…India · India Read Article

In vivo CAR-T cell generation - BioPatrika

A new frontier for treating cancer and autoimmune disease Source: Hunter et al., Science (2025) – Read the paper CAR T cell therapy has revolutionized the treatment of certain B cell cancers and shows promise in autoimmune disease. But there’s a catch—current CAR T treatments require complex, personalized manufacturing and chemotherapy pre-conditioning, making them costly […] The post In vivo CAR-T cell generation appeared first on BioPatrika.Cancer Read Article

Sphere Bio - UK Biotech Pioneer Closes Operations - BioPatrika

Sphere Bio Enters Administration: UK Biotech Pioneer Closes Operations After Financial Difficulties Cambridge-based biotechnology company Sphere Bio Limited has entered administration in August 2025, bringing to an end the operations of a once-promising single-cell analysis technology firm that had served over 400 international customers and held 135 patents. Company Background and Recent Performance Sphere Bio, […] The post Sphere Bio – UK Biot…Cambridge, England · Cambridge Read Article

Metformin is a promising host-directed therapy for tuberculosis - BioPatrika

Research Summary: Metformin limits iron availability and boosts mitochondrial ROS in host macrophages, creating a hostile environment for intracellular Mycobacterium tuberculosis. Author intervie Dr. Radheshyam and Dr. Gaurav Kumar Chaubey completed their Ph.D. degrees under the guidance of Dr. Manoj Raje at the CSIR-Institute of Microbial Technology, Chandigarh. During their doctoral studies, Dr. Radheshyam […] The post Metformin is a promisi…Environment · Chandigarh Read Article

Marathi Vidnyan Parishad’s Science Research Contest 2025 - BioPatrika

🚀 Calling All Young Innovators: Marathi Vidnyan Parishad’s Science Research Contest 2025 is Here! Since 1966, Marathi Vidnyan Parishad (MVP) has been on a mission—bringing science closer to people and inspiring the next generation of researchers. Under the leadership of Prof. J.B. Joshi, Chancellor of the Institute of Chemical Technology, Mumbai, MVP is once again […] The post Marathi Vidnyan Parishad’s Science Research Contest 2025 appeared fi…Science · Mumbai Read Article

Uncovering Cell Cycle Duration Heterogeneities within Cellular Lineages - BioPatrika

Research Summary: Cancer treatment often fails due to the cell cycle duration heterogeneities in malignant tumors. We demonstrated that transcriptional memory governs these heterogeneities and predicted ways to improve cancer treatment strategies. Author interview Ms. Kajal Charan is pursuing PhD at IIT Bombay in Computational Systems Biology after completing her master’s in Chemistry from MGS University, […] The post Uncovering Cell Cycle Durat…Mumbai · Mumbai Read Article

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