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Why molecular glue degraders are emerging as a key modality in drug discovery

Summary by Drug Discovery and Development
Targeted Protein Degradation (TPD) has  emerged as a promising modality in drug discovery, hijacking the body’s natural disposal systems to eliminate disease-causing proteins. While bivalent degraders like PROTACs have pioneered the field, demonstrating clinical promise, attention is increasingly turning toward a new upstart — Molecular Glue Degraders (MGDs). These smaller, simpler molecules offer advantages but… The post Why smaller, simpler mo…
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Drug Discovery and Development broke the news in on Monday, March 31, 2025.
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