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Beyond Hormones: Researchers Define X and Y Chromosome Contributions to Height

  • On May 19, 2025, researchers published a study in PNAS analyzing nearly one million US and UK genomes to explore height differences.
  • They studied rare cases of individuals with extra or missing X or Y chromosomes to understand genetic contributions to height.
  • The study revealed that possessing an additional Y chromosome results in a greater increase in height than having an extra X chromosome, independent of sex hormone effects.
  • Senior author Matthew Oetjens noted that this genetic factor accounts for roughly 20 percent of the typical height gap observed between males and females, indicating a modest but meaningful contribution.
  • These findings suggest that the SHOX gene on sex chromosomes partly drives male-female height differences, with hormones likely accounting for the rest.
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Scientists Find Gene That Helps Explain Why Men Are Taller Than Women

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scinexx.de broke the news in on Monday, May 19, 2025.
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