What are the first signs of perimenopause? Surprising facts

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A few weeks ago a 50-year-old woman approached me and said, “Doctor, I never thought that my biological mood changes and extreme tiredness could have such a repercussion on my marriage.” She told me that this feeling of emptiness, fatigue, anger and lack of sense of life began at age 45, and asked if menopause could begin very early. My answer was that she is probably suffering what is known as perimenopause.And what is that? It is a period of h…