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Weight loss and diabetes jabs linked to potentially fatal side effect

  • The Yellow Card Biobank initiative, a joint effort between the UK’s drug safety authority and Genomics England, has been established to explore potential genetic links in pancreatitis cases associated with GLP-1 treatments.
  • The study follows hundreds of reports of acute and chronic pancreatitis, some fatal, associated with drugs like Mounjaro, Ozempic, and Wegovy used for diabetes and weight loss.
  • Patients hospitalised with acute pancreatitis while on GLP-1 medicines are urged to report via the Yellow Card scheme and may be invited to provide saliva samples for genetic analysis.
  • MHRA data show 181 pancreatitis cases with five deaths linked to tirzepatide , 116 cases with one death linked to liraglutide, and 113 cases with one death linked to semaglutide .
  • The project aims to identify genetic factors that increase pancreatitis risk from GLP-1 drugs, enabling safer personalised treatments and potentially reducing NHS costs from adverse drug reactions.
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Last week, many media echoed a press release from the UK Regulatory Agency for Medicines and Health Products (MHRA). It called for the collaboration of people hospitalized for acute pancreatitis. The aim was to investigate whether the risk of inflammation of the pancreas in people taking GLP-1 drugs for weight loss or type 2 diabetes, such as the popular Ozempic, may be conditioned by genes. Alison Cave, responsible for safety at MHRA, estimates…

·Spain
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The number of people who have developed symptoms of poisoning due to incorrect use of slimming medication is increasing. This is reported by the Volkskrant based on figures from the National Poison Information Centre (NVIC). Last year, the NVIC received 75 reports of symptoms of poisoning from healthcare providers. Most people suffered from abdominal pain, nausea and vomiting. A year earlier, there were 41 reports. Last year, around 120,000 peop…

·Netherlands
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The number of people suffering from poisoning symptoms due to the incorrect use of slimming drugs is increasing rapidly. In 2024, the National...

·Amsterdam, Netherlands
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ITV broke the news in London, United Kingdom on Wednesday, June 25, 2025.
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