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Weight loss and diabetes jabs linked to potentially fatal side effect

UNITED KINGDOM, JUN 26 – The UK study targets genetic factors in hundreds of pancreatitis cases linked to GLP-1 drugs, with over 560 reports including six fatalities, to improve personalized patient safety.

  • The UK MHRA reported over 560 suspected pancreatitis cases linked to GLP-1 drugs, including Mounjaro, Wegovy, and Ozempic, with several deaths.
  • This follows wider adoption of GLP-1 agonists, prescribed for type 2 diabetes and weight management, used by approximately 1.5 million people in the UK.
  • Reported cases include 181 linked to tirzepatide in Mounjaro with five deaths, 116 linked to liraglutide with one death, 113 linked to semaglutide in Wegovy and Ozempic with one death, and 101 linked to exenatide with three deaths.
  • MHRA and Genomics England launched the Yellow Card Biobank to investigate potential genetic factors increasing pancreatitis risk, aiming to enable safer, personalized treatments.
  • The MHRA urges patients hospitalised with acute pancreatitis on GLP-1 drugs to report via the Yellow Card scheme, which supports research expected to improve patient safety and reduce NHS costs.
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ITV broke the news in London, United Kingdom on Wednesday, June 25, 2025.
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