Vitamin D in Tailored Doses Found to Reduce Heart Attack Risk
TARGET-D trial shows tailored vitamin D doses reduced heart attack risk by 52% in 630 heart disease patients, with doses often exceeding 5,000 IU daily, researchers said.
- At the American Heart Association annual meeting in New Orleans, investigators reported personalized vitamin D dosing cut heart attack risk by 52% in the TARGET-D randomized trial.
- Previous uniform-dose vitamin D trials tested the same dose for all participants, but this study measured participant vitamin D blood levels with more than 85% of participants starting below 40 ng/mL.
- The randomized trial enrolled 630 adults with heart disease at Intermountain Medical Center, averaging around 63 years old with 107 major heart health problems recorded.
- However, investigators found the vitamin D intervention did not lower death, heart failure or stroke risk, with benefits restricted to heart attack; Heidi May urged more clinical trials and clinician discussions.
- Because results were presented at meetings, experts urge that about half the vitamin D group required more than 5,000 IU daily, exceeding the U.S. Food and Drug Administration 800 IU daily recommendation.
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22 Articles
Tailored Doses of Vitamin D Halve Heart Attack Risk
Key Takeaways
Vitamin D's Heart Prevention Win; ATTR Depleter Does So-So; Gene Therapy Trial Hold
(MedPage Today) -- Personalized vitamin D supplementation -- often requiring 5,000 IU of vitamin D each day -- did prove to have secondary prevention benefits in the TARGET-D randomized trial presented at the American Heart Association meeting...
Common vitamin could protect some heart attack survivors, study shows – Democratic Accent
People with a history of cardiac arrest could protect themselves from future risk with one simple daily habit. A study at Intermountain Health in Salt Lake City, Utah, discovered that supplementing with vitamin D3 can significantly reduce the risk of a second heart attack in those who have already suffered one. In a large, randomized clinical trial, researchers monitored patients’ blood levels for vitamin D, while adjusting doses to “achieve opt…
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Written by Erika Watts — Fact checked by Jill Seladi-Schulman, Ph.D. Vitamin D is important for maintaining health and supports bone health, influences the immune system, and supports muscle and nerve functioning. Researchers are taking a closer look at how vitamin D can impact heart health. While prior observational studies found low levels are associated with poor cardiovascular health, trial results were mixed. Intermountain Health researc…
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