Key Alzheimer's Risk Factor May Behave Differently in Older Hispanic Adults
In a study of 17,017 older adults, Hispanic participants showed a weaker APOE ε4 link to amyloid buildup than non-Hispanic white participants.
5 Articles
5 Articles
Key Alzheimer's risk factor may behave differently in older Hispanic adults
Researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC analyzed brain imaging and clinical data from more than 17,000 participants across five major aging and Alzheimer's disease studies.
USC study reveals nuanced Alzheimer's genetic risk in Hispanic populations
Researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC analyzed brain imaging and clinical data from more than 17,000 participants across five major aging and Alzheimer's disease studies.
Alzheimer's Gene Doesn't Behave the Same Way in Everyone
On a PET scan, amyloid shows up as a wash of colour across the cortex, brighter where the sticky protein has gathered into plaques. For decades the reading of those scans has rested on a tidy assumption: carry the APOE ε4 gene variant, the strongest common genetic risk factor for late-onset Alzheimer’s, and your brain is far more likely to light up. More amyloid, more risk. The logic felt close to mechanical. A new analysis of more than 17,000 o…
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