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US Overdose Deaths Decline in 45 States Through August 2025

Overdose deaths dropped about 21% to an estimated 73,000 in 12 months through August 2025, with 45 states reporting declines amid multiple contributing factors.

  • U.S. overdose deaths fell through most of 2025, suggesting a lasting improvement in an epidemic that had been worsening for decades.
  • Overdose deaths peaked nearly 110,000 in 2022, fell a little in 2023 and then plummeted 27% in 2024, to around 80,000.
  • University of Maryland researchers point to regulatory changes in China a few years ago appear to have diminished the availability of precursor chemicals used to make fentanyl.
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  • 61% of the sources are Center
61% Center

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Winnipeg Free Press broke the news in Winnipeg, Canada on Wednesday, January 14, 2026.
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