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At least 9 dead, 11 injured in UPS plane crash and explosion at Kentucky airport

The crash involved a fully fueled UPS MD-11F cargo plane with three crew members, causing at least nine deaths and a large fire, with investigations ongoing.

  • On Tuesday, Nov. 4, a UPS cargo plane crashed shortly after takeoff from Louisville Muhammad Ali International Airport around 5:15 p.m., exploding into a fireball and trail of flames, with fire crews responding.
  • FAA records show the aircraft was a McDonnell Douglas MD‑11 freighter built in 1991, fully fueled for a long‑haul flight to Honolulu, Hawaii, with cargo intensifying the post‑crash blaze.
  • Kentucky Governor Andy Beshear said at a press briefing that at least three fatalities and 11 injured, some seriously, are being treated at area hospitals.
  • The airport was shut down and officials said operations were not expected to resume until Wednesday morning; Louisville Metro Emergency Services issued a shelter-in-place order within five miles, and Mayor Craig Greenberg warned of local road closures.
  • Happening at UPS Worldport, the crash threatens to disrupt a major hub that sorts more than 400,000 packages an hour, and UPS said the National Transportation Safety Board is leading the investigation.
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A UPS cargo plane crashed shortly after takeoff in Louisville, Kentucky yesterday afternoon.

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USA Today broke the news in United States on Tuesday, November 4, 2025.
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