Unlocking the Hidden Pocket on a Billion‑dollar Drug Target

Unlocking the hidden pocket on a billion‑dollar drug target

For years, a protein inside our cells has quietly powered billions of dollars' worth of cancer drugs. Now a team of researchers have discovered that this workhorse protein, called cereblon, in addition to its known functions, can also fine-tune which proteins live and which are sent to the cellular trash.

Unlocking hidden pocket on a billion‑dollar drug target — Harvard Gazette

Christina Woo.Photos by Veasey Conway/Harvard Staff Photographer Health Unlocking hidden pocket on a billion‑dollar drug target Scientists identify path toward making cancer drugs safer and more selective Yahya Chaudhry Harvard Correspondent March 9, 2026 5 min read For years, a protein inside our cells has quietly powered billions of dollars’ worth of cancer drugs. Now a team of researcher…

How Seeing the Protein Map Inside Cells is Changing Cancer Diagnosis - Sometimes Interesting

Cancer creates fear because it often feels unpredictable. For decades, doctors relied on tools that look at the disease from a somewhat distant perspective. They take pictures or small tissue samples, which act like taking a snapshot of a busy city from a helicopter.  You see the traffic jams, but you cannot see who is […] The post How Seeing the Protein Map Inside Cells is Changing Cancer Diagnosis appeared first on Sometimes Interesting.