Uncovering why cancer immunotherapy leads to heart inflammation

Uncovering why cancer immunotherapy leads to heart inflammation

Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by using the patient's own T-cells to target tumors. However, they can cause rare, but potentially fatal cardiac inflammation known as ICI-myocarditis. This is particularly true in the most recent ICI combination treatment of targeting proteins LAG-3 and PD-1, according to new research.