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Direct Interactions Between the Human Insula and Hippocampus During Memory Encoding

SPAIN, JUL 16 – Researchers recorded ripple brain waves in epilepsy patients during naturalistic viewing, revealing how these waves segment and organize memory episodes in the human brain.

Summary by Nature
The hippocampus is critical for encoding episodic memories, but how it interacts with cortical regions during this process remains unclear. In this study, 16 participants with implanted electrodes in the insula (217 sites) and hippocampus (131 sites) viewed emotionally valenced words and attempted to recall them. During encoding, one subset of insular neuronal populations showed changes in aperiodic activity that predicted successful recall. The…

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myscience.org broke the news in on Wednesday, July 16, 2025.
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