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New Synthetic DNA Vaccine Against Powassan Virus
MINNESOTA, AUG 9 – Researchers found a key viral pocket that disrupts Powassan virus assembly, aiding vaccine or drug development as cases rise with 26 reported in Minnesota and Wisconsin this year.
- Researchers developed and evaluated a novel DNA-based vaccine targeting the Powassan virus, with findings published on October 30, 2020.
- The vaccine development responded to increasing POWV cases in Minnesota and Wisconsin amid no existing treatments and a 300% infection rise over 16 years.
- Researchers identified a lipid pocket crucial to virus assembly, which, when disrupted by mutation, caused the virus to collapse, suggesting a drug target.
- The CDC states about 10% of severe POWV cases result in death and half suffer long-term health issues like memory loss and headaches.
- This vaccine offers a promising prevention approach amid spreading POWV infections transmitted rapidly by deer ticks, emphasizing the need for biologics and vaccination.
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18 Articles
18 Articles
Duluth News Tribune+16 Reposted by 16 other sources
U of M researchers ID weakness in Powassan virus that could lead to vaccine, treatment
The tick-borne virus, which can cause encephalitis, meningitis and death, is spreading throughout Minnesota and Wisconsin, but there are no drugs to treat or prevent it.
·Cherokee County, United States
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Coverage Details
Total News Sources18
Leaning Left0Leaning Right8Center6Last UpdatedBias Distribution57% Right
Bias Distribution
- 57% of the sources lean Right
57% Right
C 43%
R 57%
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