Researchers Reverse Muscle Stem Cell Aging with Prostaglandin E2

The hidden cost of hospitalization: muscle loss and functional decline in older adults

Many older adults fear leaving the hospital more than entering it. That’s because they know what often comes next: not a return to independent living, but a move to a care facility or a new reliance o...

Researchers reverse muscle stem cell aging with Prostaglandin E2

The population across developed countries is getting older and the associated frailty and debilitation are becoming major health problems.

Turning back time on muscle stem cells to prevent frailty from aging - Scientific Inquirer

The population across developed countries is getting older and the associated frailty and debilitation are becoming major health problems. This gradual muscle loss is accelerated by the poor capacity to repair damage and injury, especially after falls or surgeries. Low muscle mass in the elderly — known as sarcopenia — leads to increased frailty and movement problems. Patients with sarcopenia are more likely to be hospitalized and develop other …

One-Time Treatment Rejuvenates Aging Muscle Stem Cells

The world’s population is aging fast and with age comes a silent epidemic: sarcopenia, the gradual loss of muscle mass and function. This degenerative process increases frailty, reduces mobility, and raises the risk of hospitalization after injury or surgery. While exercise and nutritional interventions are widely promoted, their ability to reverse stem cell dysfunction has remained limited. Reporting in Cell Stem Cell, researchers from Sanford …

Turning Back Time on Muscle Stem Cells to Prevent Frailty From Aging

Low muscle mass in the elderly — known as sarcopenia — leads to increased frailty and movement problems. Patients with sarcopenia are more likely to be hospitalized and develop other comorbidities, largely due to falls and fractures that tend to create health declines that quickly spiral out of control. A new study demonstrates the effectiveness of treating aged mice with a naturally occurring lipid, Prostaglandin E2, which improved regeneration