Ozempic Without Nausea: Brain Cell Discovery Could Change Weight-Loss Drugs

Ozempic Without Nausea: Brain Cell Discovery Could Change Weight-Loss Drugs

Weight-loss drugs that mimic the effect of regulatory hormones on appetite and energy balance often come with a few rather uncomfortable side effects.

Tufts chemists design a next generation of weight loss drugs

Tufts researchers led by Krishna Kumar, Robinson Professor of Chemistry, have designed a new, next-generation compound with hopes that it could be more effective with fewer side effects than Ozempic and Wegovy.While weight loss drugs currently on the market and in development target one, two, or even three hormone receptors related to glucose metabolism and the desire to eat, the Tufts team has identified a fourth target that could potentially f…

Tufts Chemists Design a Next Generation Weight Loss Drug

Tufts researchers have designed a new, next-generation compound with hopes that it could be more effective with fewer side effects than the currently popular GLP-1 drugs. The new drug targets four hormone receptors simultaneously, for a combined effect that modulates hunger, pace of digestion, blood glucose, energy and fat metabolism