Chilling Platelets Could Considerably Expand Supply to Patients

Chilling Platelets Could Considerably Expand Supply to Patients

Research led by the University of Pittsburgh shows refrigerating platelets before use in patients could expand their lifespan threefold without causing any loss in function. Writing in JAMA, the investigators reported results from a trial of 989 patients who underwent platelet transfusion as part of cardiac surgery and showed that platelets refrigerated for 21 days were as effective as those stored at room temperature for five to seven days. “Pl…

Cold-Stored Platelets Safe in Cardiac Surgery

(MedPage Today) -- Extending the shelf life of platelets with refrigeration didn't hurt their hemostatic function for people undergoing complex cardiac surgery, the landmark CHIPS trial found. Platelets stored at 1-6°C (33.8-42.8°F...

Cold-stored platelets may expand options for addressing bleeding during cardiac surgery

Philip Spinella New randomised trial data support the use of cold-stored platelets to treat active bleeding during cardiac surgery, potentially helping to increase platelet shelf-life and widen accessibility for transfusions, investigators say. “Our findings could result in major international public health benefits,” said Philip Spinella (University of Pittsburgh, Pittsburgh, USA), lead author of the CHIPS study, findings of which were publishe…

Study compares cold-stored and room-temperature platelets during cardiac

A new study published in JAMA reports that cold-stored platelets may be just as effective as conventional room-temperature platelets for controlling active bleeding during cardiac surgery, potentially challenging one of the most persistent assumptions in transfusion medicine. The investigation found that cold-stored platelets, or CSPs, kept at temperatures substantially below those used for standard room-temperature […]

Trial finds chilled platelets safely expand lifesaving supplies for

University of Pittsburgh physician-scientists have reported results from an adaptive clinical trial suggesting that refrigerated platelets can remain effective for up to 21 days, potentially transforming how hospitals collect, store and deliver one of the most important therapies for patients with life-threatening bleeding. The findings, published in JAMA, indicate that chilled platelets performed as well as conventionally stored platelets in pa…