Estrogen Heightens Gut Pain Sensitivity and May Explain IBS Gender Gap

Estrogen heightens gut pain sensitivity and may explain IBS gender gap

Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort. Now, scientists at UC San Francisco may have discovered why.

Women get IBS pain more than men 'due to hormone levels'

Scientists have discovered that oestrogen activates pathways in the colon that trigger pain and make the female gut more sensitive to certain foods

Women more likely to suffer IBS pain 'due to their hormones', researchers find - The Mirror

According to the study, certain hormones can trigger pain in the colon

This newfound cascade of events may explain some female gut pain

Gut problems like irritable bowel syndrome are often worse in women. A mouse study reveals a pain pathway involving estrogen, gut cells and bacteria.

Why are women more likely to get irritable bowel syndrome? New study provides clues

Cells in the guts of female mice respond to estrogen by increasing pain signaling, researchers find