Targeted Phages Curb Crohn's-Linked Gut Inflammation by Disabling Harmful E. Coli Traits
The phages reduced inflammation in lab and stool-sample tests and may help identify Crohn’s patients most likely to benefit.
6 Articles
6 Articles
Mcmaster researchers develop targeted phage therapy for inflammatory bowel disease
A research team at McMaster University has developed a targeted approach to treating inflammatory bowel disease (IBD) using bacteriophages, viruses that infect specific bacteria, to disarm harmful microbes without disrupting the broader gut ecosystem.
Targeted phages curb Crohn's-linked gut inflammation by disabling harmful E. coli traits
A research team at McMaster University has developed a targeted approach to treating inflammatory bowel disease (IBD) using bacteriophages, viruses that infect specific bacteria, to disarm harmful microbes without disrupting the broader gut ecosystem.
International researchers take a big step towards addressing this increasingly common pathology
When patients with Crohn’s disease or ulcerative colitis suffer from an inflammatory outbreak, doctors frequently turn to antibiotics to try to stop the bacteria that trigger the pathology. The problem is that these drugs act as a cluster bomb: they destroy both harmful microbes and beneficial bacteria, further aggravating the imbalance of intestinal flora and leaving long-term sequelae. Now, an innovative international study seems to have found…
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BIOENGINEER.ORGMcMaster scientists deploy harmless viruses to fight inflammatory bowel
A groundbreaking study from McMaster University has unveiled a precision bacteriophage therapy aimed at treating inflammatory bowel disease (IBD) by selectively targeting adherent-invasive Escherichia coli (AIEC), bacteria implicated in Crohn’s disease inflammation. Published in Science Translational Medicine, this interdisciplinary research combines microbiome science and engineering to develop a viral-based intervention that suppresses harmful…
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