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Targeting ZMIZ1 Induces Differentiation in Acute Myeloid Leukemia via Chromatin Remodeling
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Targeting ZMIZ1 Induces Differentiation in Acute Myeloid Leukemia via Chromatin Remodeling
Researchers identified Zinc finger MIZ domain-containing protein 1 (ZMIZ1) as a previously unrecognized transcriptional co-regulator that enforces differentiation blockade in AML from a targeted CRISPR-Cas9 screen. [Signal Transduction and Targeted Therapy] Full Article
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